A few of the movie villains I have enjoyed a lot in my movie watching across the years:

"from Hell's heart, I stab at thee! For hate's sake, I spit my last breath at thee! "
The late Ricardo Montalban was magnificent as the malignant Khan, a genetic superman bent on exacting revenge on Kirk for the death of his wife. Khan was a steely villian with old world charm and a vocabulary to match, plotting galactic domination with the sophistication of an English Duke.

"You want chaos? *I'm* the chaos"
You have to like this one because Armand Assante gave life, intensity and purpose to a character that was otherwise poorly defined in the script. Assante manages to take his few lines in the movie and convey the anguish and rage of Rico, betrayed by his clone brother, Judge Dredd. He reveled in chaos and you felt him, big time.

"I will destroy any man who tries to take what I got! "
Mr. T puts on an awesomely impressive display of malevolence. He very effectively conveys brute, unstoppable fury. Whenever he was on screen, you knew pain was not far behind.

"You may wake up one day and find yourself extinct."
One way you know Steven Dorf did a good job in this film was that you genuinely did not like Frost. He wasn't just an evil vampire, he was a real a**hole about it too.
So those are a few of my pics, which I think are pretty good. Have you got a better four villains? Top these.